The present study aims at preparing an Emulgel formulation of Meloxicam using emulsifiers and various gelling agents along with the use of. PDF | Emulgel is one of the recent technologies in NDDS used for dual control release of emulsion and gel for topical use. The stability of. PDF | Topical therapies in cream, ointment, gel and lotion formulation, are an important component of dermatological therapeutic.

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Published online Sep 1. Lea and Febiger; All the prepared emulgels showed acceptable physical properties concerning color, homogeneity, consistency, spreadability, and pH value. Support Center Support Center. This article has been cited by other articles in PMC. Rheological studies revealed that the CHL emulgels exhibited a shear-thinning behavior with thixotropy. The Theory and Practice of Industrial Pharmacy. National Center for Biotechnology InformationU. Stability studies showed that the physical appearance, rheological properties, drug release, and antifungal activity in all the prepared emulgels remained unchanged upon storage for 3 months.

Optimization of chlorphenesin emulgel formulation

The drug release from all the emulgels was found to follow diffusion-controlled mechanism. Analysis of data on the medicament release from ointments. Development of a thermoreversible gel for controlled-release ocular delivery of diclofenac sodium. They also exhibited higher drug release and antifungal activity than the CHL powder. This study was conducted to develop an emulgel formulation of chlorphenesin CHL using 2 types of gelling agents: Author information Article notes Copyright and License information Disclaimer.


Bioavailability of salbutamol sulphate from different suppository formulations. Received Dec 31; Accepted May Medical Applications of Controlled Release.

Az J Pharm Sci. Formulation formuation evaluation of topical preparations containing phenol and local vesicants.

It was found that the emulsifying agent concentration had the most pronounced effect on the drug release from the emulgels followed by the oil phase concentration and finally the type of the gelling agent. Blackwell Scientific Publications; Preparation of an emulgel for treatment of aphthous ulcer on the basis of carbomers. A study of shear and compression deformations on hydrophilic gels of tretinoin.

Abstract This study was conducted to develop an emulgel formulation of chlorphenesin CHL using 2 types of gelling agents: Egypt J Pharm Sci. As a general conclusion, it was suggested that the CHL emulgel formulation prepared with HPMC with the oil phase concentration in its low level and emulsifying agent concentration in its high level was the formula of choice since it showed the highest drug release and antifungal activity.


Marcel Dekker Inc; Encyclopedia of Pharmaceutical Technology.

The prepared emulgels were evaluated for their physical appearance, rheological behavior, drug release, antifungal activity, and stability. Swarbrick J, Boylan JC, editors. Formulation and stability of chloramphenicol gel and formulayion. The Pharmaceutical Press; Commercially available CHL topical powder was used for comparison.

Optimization of chlorphenesin emulgel formulation

forkulation Please review our privacy policy. The influence of the type of the gelling agent and the concentration of both the oil phase and emulsifying agent on the drug release from the prepared emulgels was investigated using a 2 3 factorial design. The Complete Drug Reference. Transdermal controlled release systems.